There is some evidence to suggest glycolytic activity is increased with age, with an increase in pyruvate kinase activity,70 which would be predicted if ageing was associated with constitutive PI3K activity. Hyperlactataemia is an indie predictor of mortality in both … Continue reading There is some evidence to suggest glycolytic activity is increased with age, with an increase in pyruvate kinase activity,70 which would be predicted if ageing was associated with constitutive PI3K activity